刘志强，医学博士，主任医师，教授，博士研究生导师，上海市优秀学术带头人。现任美高梅附属第一妇婴保健院麻醉科主任，59599aa美高梅麻醉与围术期医学系常务副主任。以第一或通讯作者发表 SCI 论文50余篇，核心期刊论文60余篇；主编专著3部、副主编专著5部，以执笔人或编写组成员身份参与制订多部国内临床指南及专家共识；主持及完成国家自然科学基金面上项目、上海市科委、上海市卫生健康委等课题18项。第一完成人获得上海医学科技进步奖三等奖（2019年），上海科普教育创新奖科普贡献奖（个人）二等奖（2021年），入选上海市科委优秀学术带头人计划（2022 年）。
Zhiqiang Liu, Doctor of Medicine, chief physician, professor, doctoral supervisor, and outstanding academic leader in Shanghai. Director of the Department of Anesthesiology, Shanghai First Maternity and Infant Hospital affiliated to Tongji University, Executive Deputy Director of the Department of Anesthesiology and Perioperative Medicine of Tongji University School of Medicine. He published more than 50 SCI papers as the first or corresponding author and more than 60 papers in core journals, edited 3 monographs as chief editor and 5 monographs as deputy editor, participated as a writer or member of the writing group in the formulation of several clinical guidelines and expert consensus, hosted and undertook 18 projects such as National Natural Science Foundation Project, Shanghai Science and Technology Commission, and Shanghai Health Commission, won the third prize for Shanghai Medical Science and Technology Award as the first completer (2019), the second prize for popular science contribution (individual) in Shanghai Science Popularization Education Innovation Award (2021), and selected for the Shanghai Science and Technology Commission’s Outstanding Academic Leader Program (2022).
在研科研项目：
上海市科委，2022年度“科技创新行动计划”优秀学术带头人，22XD1402400，基于突触外GABAA受体亚基功能探究产后抑郁发生的神经微环路机制，2022.9.1-2025.8.31，40万、在研、主持
上海市科委自然科学基金，22ZR1449300，七氟烷经选择性抑制GluN2D发挥快速抗抑郁的作用机制研究，2022.04.01-2025.03.31，20万、在研、主持
浦东新区卫健委联合攻关项目，PW2021D-01，围产期抑郁“早期筛查-优化管理-联合诊治”一体化防治体系的构建，2021.07.01-2024.06.30，30万、在研、主持
横向课题，苯磺酸瑞马唑仑静脉麻醉对宫腔镜手术患者血流动力学及麻醉效果影响的随机对照研究，2022.8.25-2024.8.25，16万、在研、主持
近年发表的论文：
Binglu Ye, Yawei Yuan, Rui Liu, Haitao Zhou, Yujie Li, Zhihao Sheng, Tianyu Li, Bing Zhang, Zhendong Xu, Yang Li, Zhiqiang Liu. Restoring Wnt signaling in a hormone-simulated postpartum depression model remediated imbalanced neurotransmission and depressive-like behaviors. Mol Med. 2023, 29(1):101.（通讯作者） IF: 6.3821
Yujie Li, Weijia Du, Rui Liu, Guiying Zan, Binglu Ye, Qian Li, Zhihao Sheng, Yawei Yuan, Yujie Song, Jinggen Liu, Zhiqiang Liu. Paraventricular nucleus-central amygdala oxytocinergic projection modulates pain-related anxiety-like behaviors in mice. CNS Neurosci Ther. 2023. doi: 10.1111/cns.14282. Online ahead of print.（通讯作者） IF: 7.034
Shuangqiong Zhou, Xiuhong Cao, Yao Zhou, Zhendong Xu, Zhiqiang Liu. Ultrasound assessment of gastric volume in parturients after high-flow nasal oxygen therapy. Anesth Analg. 2023, 137(1):176-181.（通讯作者） IF: 6.627
Yuanxi Li, Bing Zhang, Xiaochuan Pan, Yihong Wang, Xuying Xu, Rubin Wang, Zhiqiang Liu. Dopamine Mediated Major Depressive Disorder in the Neural Circuit of VTA-NAc-mPFC: From Biological Evidences to Computational Models. Front Cell Neurosci. 2022, 16: 923039.（通讯作者）IF: 6.147
Yi J, Li Y, Yuan Y, Xu Z, Song Y, Ye B, Zhao Q, Yang Y, Du W, Liu Z. Comparison of labor analgesia efficacy between single-orifice and multiorifice wire-reinforced catheters during programmed intermittent epidural boluses: a randomized controlled clinical trial. Reg Anesth Pain Med. 2023, 48(2):61-66.（通讯作者） IF: 5.564
Lin R, Lu Y, Luo W, Zhang B, Liu Z, Xu Z. Risk factors for postpartum depression in women undergoing elective cesarean section: A prospective cohort study. Front Med (Lausanne). 2022 Sep 28;9:1001855.（共同通讯）IF: 5.058
Weijia Du#; Lulong Bo#; Zhendong Xu; Zhiqiang Liu. Childbirth Pain, Labor Epidural Analgesia, and Postpartum Depression: Recent Evidence and Future Directions. J Pain Res. 2022:15 3007–3015.（通讯作者） IF: 2.832
Yilu Zhou, Zhendong Xu; Zhiqiang Liu. Impact of Neutrophil Extracellular Traps on Thrombosis Formation: New Findings and Future Perspective. Front Cell Infect Microbiol. 2022, 12: 910908.（通讯作者）IF: 6.073 (Review)
Chen X, Zhang Y, Ni X, Liu Z. Effects of labour analgesia with different concentrations of ropivacaine on maternal body temperature and inflammatory factor: A randomised controlled study. Anaesth Crit Care Pain Med. 2022, 41(2): 101030. （通讯作者）IF: 7.025
Xiuhong Cao, Ye Luo, Shuangqiong Zhou, Qingsong Zhao, Xuewei Qin, Zhendong Xu, Zhiqiang Liu. Twin growth discordance and risk of postpartum hemorrhage: A retrospective cohort study. Front Med (Lausanne). 2022, 9: 876411.（通讯作者）IF: 5.058
Weijia Du, Yujie Song, Jiang L, Xianjin Zhou, Zhendong Xu, Zhiqiang Liu. Comparison of Prophylactic Norepinephrine and Phenylephrine Infusions During Spinal Anaesthesia for Primary Caesarean Delivery in Twin Pregnancies: A Randomized Double-Blinded Clinical Study. Drug Des Devel Ther. 2022, 16: 789-798.（通讯作者）IF: 4.319
Weijia Du, Yujie Song, Qingsong Zhao, Zhendong Xu, Zhiqiang Liu. The effect of open-end versus closed-end epidural catheter design on injection pressure and dye diffusion under various programmed intermittent epidural delivery rates: an in vitro study. Int J Obstet Anesth. 2022, 51: 103252.（通讯作者）IF: 3.282
Yujie Song, Weijia Du, Yiyi Tao, Qian Li, Fuyi Shen, Zhendong Xu, Zhiqiang Liu. Optimum programmed intermittent epidural bolus interval time between 8 mL boluses of Ropivacaine 0.1% with sufentanil 0.3 μg/mL with dural puncture epidural technique for labor analgesia: A biased-coin up-and-down sequential allocation trial. J Clin Anesth, 2022, 79:110698.（通讯作者）IF: 9.375
Gui-Ying Zan, Xiang Sun, Yu-Jun Wang, Rui Liu, Chen-Yao Wang, Wei-Jia Du, Liu-Bin Guo, Jing-Rui Chai, Qing-Lin Li, Zhi-Qiang Liu, Jing-Gen Liu. Amygdala dynorphin/κ opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress. Acta Pharmacol Sin. 2022, 43(3): 577-587.（通讯作者）IF: 7.169
Zhendong Xu, Zhiqiang Liu. In Response. Anesth Analg. 2021, 133(3):e40-e41.（通讯作者）IF: 6.627 (Comment)
Xudong Chen, Mingze Zhou, Sensen Zhang, Jian Yin, Ping Zhang, Xujun Xuan, Peiyi Wang, Zhiqiang Liu, Boda Zhou, Maojun Yang. Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2. Cell Discov. 2021, 7(1):106. （共同通讯）IF: 38.079
Yilu Zhou, Weimin Tao, Fuyi Shen, Weijia Du, Zhendong Xu, Zhiqiang Liu. The Emerging Role of Neutrophil Extracellular Traps in Arterial, Venous and Cancer-Associated Thrombosis. Front Cardiovasc Med. 2021, 8: 786387.（通讯作者）IF: 5.846 (Review)
Gui-Ying Zan, Yu-Jun Wang, Xue-Ping Li, Jun-Fan Fang, Song-Yu Yao, Jun-Ying Du, Qian Wang, Xiang Sun, Rui Liu, Xiao-Mei Shao, Jian-Dong Long, Jing-Rui Chai, Ying-Zhi Deng, Ye-Qing Chen, Qing-Lin Li, Jian-Qiao Fang, Zhi-Qiang Liu, Jing-Gen Liu. Amygdalar κ-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence. Cell Rep. 2021, 37(5): 109913. （共同通讯）IF: 9.995
Yujie Song, Weijia Du, Shuangqiong Zhou, Yao Zhou, Yibing Yu, Zhendong Xu, Zhiqiang Liu. Effect of Dural Puncture Epidural Technique Combined With Programmed Intermittent Epidural Bolus on Labor Analgesia Onset and Maintenance: A Randomized Controlled Trial. Anesth Analg.2021, 132(4): 971-978.（通讯作者）IF: 6.627
Yilu Zhou, Wei Chen, Shuangqiong Zhou, Yiyi Ta, Zhendong Xu, Zhiqiang Liu. Comparison of different approaches to combined spinal epidural anesthesia (CSEA) under the guidance of ultrasound in cesarean delivery of obese patients: a randomized controlled trial. Eur J Med Res. 2021, 26(1): 106. IF: 4.981
Bing Zhang, Xili Yang, Luyu Ye, Rui Liu, Binglu Ye, Weijia Du, Fuyi Shen, Qian Li, Fan Guo, Jinqi Liu, Fei Guo, Yang Li, Zhendong Xu, Zhiqiang Liu. Ketamine Activated Glutamatergic Neurotransmission by GABAergic Disinhibition in the Medial Prefrontal Cortex. Neuropharmacology. 2021, 194:108382.（通讯作者）IF: 5.273
Xiu Ni, Meng-Zhu Li, Shuang-Qiong Zhou, Zhen-Dong Xu, Yue-Qi Zhang, Yi-Bing Yu, Jing Su, Li-Min Zhang, Zhi-Qiang Liu. Accuro ultrasound-based system with computer-aided image interpretation compared to traditional palpation technique for neuraxial anesthesia placement in obese parturients undergoing cesarean delivery: a randomized controlled trial. J Anesth. 2021, 35(4):475-482. （通讯作者）IF: 2.931
Rong Lin, Peng Shi, Haibing Li, Zhiqiang Liu, Zhendong Xu. Association between epidural analgesia and indications for intrapartum caesarean delivery in group 1 of the 10-group classification system at a tertiary maternity hospital, Shanghai, China: a retrospective cohort study. BMC Pregnancy Childbirth. 2021, 21(1):464.（共同通讯）IF: 3.105
Shuang-Qiong Zhou, Yao Zhou, Xiu-Hong Cao, Xiu Ni, Wei-Jia Du, Zhen-Dong Xu, Zhi-Qiang Liu. The efficacy of high flow nasal oxygenation for rapid sequence induction in pregnancy: a prospective randomised clinical trial. Eur J Anaesthesiol. 2021, 38(10): 1052-1058.（通讯作者）IF: 4.183
Wei Liu, Qian Li, Binglu Ye, Hang Cao, Fuyi Shen, Zhendong Xu, Weijia Du, Fei Guo, Jinqi Liu, Tianyu Li, Bing Zhang, Zhiqiang Liu. Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex. Front Psychiatry. 2020, 11:837.（通讯作者）IF: 5.435
Yan Lu, Zhendong Xu, Fuyi Shen, Rong Lin, Haibing Li, Xiang Lv, Zhiqiang Liu. Propofol protects against TNF-α-induced blood-brain barrier disruption via the PIM-1/eNOS/NO pathway. Curr Neurovasc Res. 2020, 17(4):471-479.（通讯作者）IF: 2.294
Xiubin Chen, Xiu Ni, Yueqi Zhang, Hong Liu, Zhiqiang Liu. The association of labor epidural analgesia with low concentration of ropivacaine and maternal fever: A retrospective study. J Clin Anesth. 2020, 65:109613.（通讯作者）IF: 9.375
Yao Zhou, Weimin Tao, Xuewei Qin, Rong Lin, Zhiqiang Liu, Zhendong Xu. Evaluating coagulation status with thromboelastography in a woman with antiphospholipid syndrome and sepsis: a case report. J Anesth. 2020, 34(5):781-785.（共同通讯） IF: 2.931
Sensen Zhang,Yang Liu,Bing Zhang, Jun Zhou, Tianyu Li, Zhiqiang Liu, Yang Li, Maojun Yang. Molecular insights into the human CLC-7/Ostm1 transporter. Science Advances. Sci Adv. 2020, 6(33):eabb4747.（共同通讯）IF: 14.957
Qian Li, Bing Zhang, Hang Cao, Wei Liu, Fei Guo, Fuyi Shen, Binglu Ye, Huan Liu, Yang Li, Zhiqiang Liu. Oxytocin Exerts Antidepressant-like effect by potentiating dopaminergic synaptic transmission in the mPFC. Neuropharmacology. 2020, 162:107836.（通讯作者）IF: 5.273
Zhi-Qiang Liu, Wei-Jia Du, Shang-Long Yao. Enhanced recovery after cesarean delivery: a challenge for anesthesiologists. Chin Med J (Engl). 2020, 133(5):590-596.（第一作者）IF:2.624
Shuang-Qiong Zhou, Jing Wang, Wei-Jia Du, Yu-Jie Song, Zhen-Dong Xu, Zhi-Qiang Liu. Optimum interval time of programmed intermittent epidural bolus of ropivacaine 0.08% with sufentanyl 0.3 μg/mL for labor analgesia: a biased-coin up-and-down sequential allocation trial. Chin Med J (Engl). 2020, 133(5):517-522.（通讯作者）IF: 6.133
Zhou X, Li J, Deng S, Xu Z, Liu Z. Ropivacaine at different concentrations on intrapartum fever, IL-6 and TNF-α in parturient with epidural labor analgesia. Exp Ther Med. 2019, 17(3):1631-1636.（通讯作者）IF: 2.751
Li M, Ni X, Xu Z, Shen F, Song Y, Li Q, Liu Z. Ultrasound Assisted Technology Versus the Conventional Landmark Location Methodin Spinal Anesthesia for Cesarean Delivery in Obese Parturients: A Randomized Controlled Trial. Anesth Analg. 2019, 129(1):155-161.（通讯作者）IF: 6.627
Chen X, Chen F, Zhao Q, Zhang L, Liu Z. Ultrasonographic measurement of antral area for estimating gastric fluid volume in pregnant women. J Clin Anesth. 2019, 53:70-73.（通讯作者）IF: 9.375
Shen FY, Song YC, Guo F, Xu ZD, Li Q, Zhang B, Ma YQ, Zhang YQ, Lin R, Li Y, Liu ZQ. Cognitive Impairment and Endoplasmic Reticulum Stress Induced by Repeated Short-Term Sevoflurane Exposure in Early Life of Rats. Front Psychiatry. 2018, 9:332.（通讯作者）IF: 5.435
Du W, Xu Z, Wang W, Liu Z. A case of anosmia and hypogeusia as a complication of propofol. J Anesth. 2018, 32(2):293-296.（通讯作者）IF: 2.931
Xu Z, Liu Z, Zhang Y, Jin C, Shen F, Yu Y, Cheek T, Onuoha O, Liang G, Month R, Atkins J, Tran KM, Wei H. S100β in Newborns after C-Section with General versus Epidural Anesthesia: a prospective observational study. Acta Anaesthesiol Scand. 2018, 62(3):293-303.（共同通讯）IF: 2.274
