美高梅转化医学高等研究院副研究员
Clinical Immunology Communications，Immunobiology等期刊审稿人
Associate Professor at the Institute of Translational Medicine, Tongji University
Reviewers for Clinical Immunology Communications and Immunobiology
研究成果简介：
通过系统性研究免疫细胞在肠癌微环境中的功能失调，涵盖其迁移、浸润及分化过程，揭示肠癌发生发展的免疫学分子机制。基于这些发现，研发靶向免疫干预策略，重塑肠道免疫微环境，增强抗肿瘤免疫反应，进而为肠癌的精准治疗提供新的解决方案。迄今共发表研究论文20余篇，以第一或通讯作者（含共同）身份在Immunity (2019)，STTT (2022), Advanced Science (2024), Nature communications (2024), Cancer Immunology Research (2021), Oncogene (2023), PLoS Biology (2018)等国际知名学术期刊发表论文。研究成果被Nature，Science，JAMA等作为亮点推荐。主持包括国自然面上、青年，上海市科委面上在内的多项科研项目。
Through a systematic investigation of immune cell dysfunction in the colorectal cancer microenvironment—covering processes such as migration, infiltration, and differentiation—we aim to uncover the immune molecular mechanisms driving colorectal cancer development. Building on these insights, we seek to develop targeted immune intervention strategies to reshape the intestinal immune microenvironment, enhance anti-tumor immune responses, and provide innovative solutions for the precision treatment of colorectal cancer. To date, over 20 research papers have been published, with the researcher serving as first or corresponding author (including co-first authorship) in leading international journals such as Immunity (2019), STTT (2022), Advanced Science (2024), Nature Communications (2024), Cancer Immunology Research (2021), Oncogene (2023), and PLoS Biology (2018). The research findings have been highlighted by journals such as Nature, Science and JAMA. The researcher has also led multiple research projects, including those funded by the National Natural Science Foundation of China (NSFC), as well as the Shanghai Municipal Science and Technology Commission.
主持科研项目：
1.国家自然科学基金面上项目，49万元，2025.01-2028.12
2.国家自然科学基金面上项目，56万元，2022.01-2025.12
3.上海市科委自然科学基金面上滚动项目，50万元，2024.12-2027.11
4.上海市科委自然科学基金面上项目，20万元，2021.07- 2024.06
5.国家自然科学基金青年项目，20万元，2018.01-2020.12
6.上海市第十人民医院攀登人才计划，20万元，2021.01- 2022.12
7.上海市第十人民医院国自然培育面上A类，10万元，2020.01-2022.12
