上海人类学学会医学人类学专业委员会
中国学位与研究生教育学会专家库专家
中国产前诊断杂志电子版,青年编委;
担任过多个SCI期刊的审稿人,Environmental international (IF 11.8),Chemosphere (IF 8.8), Environmental pollution(IF 8.9)等.
Shanghai Anthropological Society Medical anthropology professional committee
Expert of Chinese Society of Degree and Graduate Education
Chinese Journal of Prenatal Diagnosis electronic Edition, Youth Editorial Board
Peer Reviewer for many SCI journals, for instance, Environmental international (IF 11.8),Chemosphere (IF 8.8) and Environmental pollution(IF 8.9), et al
59599aa美高梅硕士研究生导师。以第一或者通讯作者共发表SCI论文7篇,其中中科院1区的3篇,累计影响因子40。合著英文专著1本。作为项目负责人主持科研项目4项,包括国家自然科学基金项目1项,上海市母胎重点实验室开放课题1项和校局级项目2项。曾在国外分子知名分子生物实验室参与研发,参与研发构建150万人的遗传基因数据库。长期从事第二代测序及分子诊断,分析了超过5000例的遗传罕见病基因测序数据。首次解析了环境微塑料污染对于胎盘及胎儿的毒性分子机制,成果表与环境健康领域中科院1区Science of The Total Environment(IF=9.8)杂志上。
Postgraduate tutor of Tongji University School of Medicine. A total of 7 SCI papers were published as the first or corresponding author, including 3 papers from the 1st District of the Chinese Academy of Sciences, with a cumulative impact factor of 40. Co-authored 1 English monograph. As the project initiator, guide over 4 scientific research projects, including 1 project of the National Natural Science Foundation, 1 open project of Shanghai Key Laboratory of Maternalism and 2 projects at the school bureau level. Participated in research and development in well-known global molecular diagnosis laboratory, and participated in the development of the genetic gene database of 1.5 million people. Experienced in next generation sequencing and molecular diagnosis, and have analyzed gene sequencing data of more than 5,000 cases of genetic rare diseases. Elucidated the molecular mechanism of toxicity of microplastic impact on placenta and fetus for the first time, and the results were published in the journal Science of The Total Environment (IF = 9.8, the 1st District of the Chinese Academy of Sciences).
代表性论文:
Representative publications:
1) Chen Guangquan, Xiong Shiyi,et al. Maternal exposure to polystyrene nanoparticles retarded fetal growth and triggered metabolic disorders of placenta and fetus in mice. Science of the Total Environment , 2023, 854: 158666 (IF:9.8)
2)Chen Guangquan, van Straalen N M, Roelofs D. The ecotoxicogenomic assessment of soil toxicity associated with the production chain of 2, 5- furandicarboxylic acid (FDCA), a candidate bio-based green chemical building block. Green Chemistry. 2016; 18(16):4420-4431(IF:9.8)
3)Chen Guangquan, den Braver M W, van Gestel C A, et al. Ecotoxicogenomic assessment of diclofenac toxicity in soil. Environmental Pollution. 2015; 199(C):253-260(IF:8.9)
4)Qiao J, Chen Y, Lu Y, Wang T, Li X, Qin W, Li A, Chen Guangquan. A Syndrome of Variable Allergy, Short Stature, and Fatty Liver. Frontiers in Genetics. 2022; 12:784135(IF:3.7)
5)Chen, Guangquan, de Boer T E, Wagelmans M, et al. Integrating transcriptomics into triad-based soil-quality assessment. Environmental toxicology and chemistry. 2014; 33(4):900-909(IF:4.1)
6)Xi Y*, Chen Guangquan*,Lei C, et al. Expanded carrier screening in Chinese patients seeking the help of assisted reproductive technology. Molecular genetics & Genomic medicine. 2020; 8(9):e1340(IF:2.0)
7)Chen Guangquan*, Xiong S*, Zou G, et al. A 6.3 Mb maternally derived microduplication of 20p13p12.2 in a fetus with Brachydactyly type D and related literature review. Molecular Cytogenetics. 2022; 15(1):6 (IF:1.3)
8)Swart E, de Boer T E, Chen Guangquan, et al. Species-specific transcriptomic responses in Daphnia magna exposed to a bio-plastic production intermediate. Environmental Pollution. 2019; 252(Pt A):399-408(IF:8.9)
9)Kong L, Li S, Zhao Z, Feng J, Chen Guangquan, et al. Haplotype-Based Noninvasive Prenatal Diagnosis of 21 Families With Duchenne Muscular Dystrophy: Real-World Clinical Data in China. Frontiers in Genetics. 2021; 12:791856(IF:3.7)
10)Zhu D, Wei X, Chen Guangquan, et al. Chromosomal abnormalities in recurrent pregnancy loss and its association with clinical characteristics[J]. Journal of Assisted Reproduction and Genetics, 2023: 1-8.(IF:3.1)
11)Xiong S, Wu F, Chen Guangquan,, et al. Prenatal Phenotypical Discrepancy in Monozygotic Twins with Tuberous Sclerosis Complex. Maternal-Fetal Medicine, 2022, 4(04): 286-289.(IF:1.0)
12)Qiu hao, li jingjing, Chen Guangquan et al , 微/纳塑料穿透机体生物屏障及其健康效应, Chinese Science Bulletin (科学通报), 2023, ISSN 0023-074X (核心期刊, IF:1.1)