获奖及荣誉 (Awards and honors)
第三届上海市医树奖临床医学科技创新奖三等奖
2020年享受国务院特殊津贴专家
2019年国家百千万工程国家级人才
2019年被授予:国家突出贡献中青年专家
2015年上海市领军人才
2015年上海市优秀学术带头人。
2013年上海市卫生系统优秀学科带头人(新百人)
2013年上海市优秀硕士学位论文,指导导师
2013年复旦大学优秀硕士学位论文,指导导师
2012年复旦大学研究生教学成果二等奖“临床免疫学”
2012年复旦大学附属妇产科医院优秀科研人员奖
作为第三完成人获:
2014年度中华医学科技二等奖
2014年度上海市医学科技二等奖
2007年度教育部科学技术进步二等奖
2006年度中华医学科技三等奖
2006年度上海市科技进步二等奖
2005年度上海市医学科技二等奖
2004年度上海市医学科技三等奖
承担科研项目 (Research Projects)
国家自然科学基金面上项目82271701:烟酰胺磷酸核糖转移酶NAMPT通过N-GSDMD调节早孕期M1型蜕膜巨噬细胞稳态的机制研究,52万,2023.01-2026.12,项目负责人。
国家自然科学基金面上项目82071653:谷氨酰胺代谢通路在蜕膜化过程中的调控作用及机制研究,55万,2021.01-2024.12,项目负责人。
国家自然科学基金重点项目81730039:内分泌-免疫调节失常诱发蜕膜化障碍与母-胎免疫紊乱致妊娠失败的机制研究,286万,2018.01-2022.12,项目负责人。
国家自然科学基金面上项目81671460:琥珀酸通过IL-1β通路调节滋养细胞侵袭的功能及机制研究,75万,2017.01-2020.12,项目负责人。
国家自然科学基金面上项目31170870:滋养细胞通过分泌TSLP介导蜕膜γδT细胞免疫调节功能,55万,2012.01-2015.12,项目负责人。
科技部重点专项子课题2017YFC1001401:人类胚胎着床调控及相关重大妊娠疾病发生机制,123万,2017.07-2021.6,课题负责人
科技部863项目子课题2014AA020706:避孕抗生育疫苗的研发,145万,2014.01-2016.12,课题负责人。
上海市优秀学术带头人计划15XD1500900:mir-184转基因小鼠流产模型的建立及研究,40万,2015.07-2018.06,项目负责人。
上海市卫生系统优秀学科带头人培养计划: 绒毛mir-184高表达在反复自然流产中的作用及机制研究,90万,2013.11-2016.10,项目负责人。
上海领军人才:mir-184转基因小鼠流产模型的建立及研究,50万,2015.05-2018.04,项目负责人。
上海市教育委员会重点项目SOF157001:绒毛mir-184高表达在反复自然流产中的作用及机制研究,16万,2014.01-2016.12,项目负责人。
上海市科委医学引导项目:环孢素A防治反复自然流产的临床研究,20万,2013.07-2016.06,项目负责人。
上海市自然科学基金项目102R1405100:蜕膜γδT细胞在母-胎免疫耐受中的调节性作用,10万,2010.04-2012.03,项目负责人。
教育部新教师基金200802461019:孕期扩增的Th17细胞在母-胎免疫调节中的作用,3.6万,2009.01-2010.12,项目负责人。
国家重点基础研究计划(973计划)项目2015CB943300:母-胎界面交互对话异常致妊娠相关重大疾病的分子机制,100万,2015.01-2019.12,骨干成员。
国家自然科学基金重点项目30730087:妊娠期调节性T细胞来源及在母-胎免疫耐受中的作用,150万,2008.01-2010.12,主要参与者。
国家自然科学基金重大国际(地区)合作交流项目30910103909:TSLP 在免疫耐受形成中的调节作用,80万,2010.01-2012.12,主要参与者。
国家自然科学基金面上项目81070537:环孢素A诱导母-胎界面Th2型免疫优势的分子机制,29万,2011.01-2013.12,主要参与者。
上海市浦江人才计划基金10PJ1401600:环孢素A通过CCL2/CCR2诱导母胎界面Th2型免疫偏移,20万,2010.01-2012.12,主要参与者。
国家重大科学研究计划项目2006CB944009:生殖细胞健康与母胎识别及免疫豁免的分子基础:蜕膜化相关基因的筛选、调节及功能,231万,2007.1-2011.12,主要参与者。
国家自然科学基金面上项目30470264:过继转输胚胎抗原耐受性T细胞对妊娠预后影响的分子机制,22万,2005.1-2007.12,主要参与者。
申请专利 (Application for Patent)
金莉萍 徐向红 郝璠 唐林晨 上海市第一妇婴保健院。PRMT3在诊断或治疗复发性自然流产中的应用。专利号:202110414167.2 专利授权日期:2022-09-20
金莉萍 赵健元 王晓辉 上海市第一妇婴保健院。琥珀酸在诊断或治疗自然流产中的应用。专利申请号:202110181710.9 专利申请日期:2021-10-18
金莉萍 郑青亮 上海市第一妇婴保健院。一种用于捕获RNAm1A修饰结合蛋白的探针设计及方法。专利申请号:201911189212.8 专利申请日期:2019-11-28
郑青亮 金莉萍 上海市第一妇婴保健院。用于捕获胎儿特有DNA甲基化修饰结合蛋白的探针及方法。专利申请号:201911188858.4 专利申请日期:2019-11-28
董晨 倪凌 金莉萍 蔡东莉 清华大学和上海市第一妇婴保健院。体外大量扩增恶性肿瘤腹水浸润的淋巴细胞的方法。专利申请号:201911318914.1 申请日期:2019-12-19
金莉萍 张媛 周济 张进平 李明清 周文洁 美高梅附属第一妇婴保健院。 miR-184在自然流产预警中的作用。专利申请号:2018100681472,专利申请日期:2018-1-24
李明清 周文洁 张冰 金莉萍 孙建松 杨慧丽 复旦大学附属妇产科医院. 原人参二醇PPD在制备子宫内膜异位症药物中的应用 专利申请号:201810002886.1专利申请日: 2018-01-02
李明清 周文洁 金莉萍 复旦大学附属妇产科医院. 1,6-二磷酸果糖在制备自然流产保胎药物中的应用 专利申请号:201810225540.8 专利申请日:2018-03-19
周文洁 李明清 金莉萍 伍科 常凯凯 谢锋 贺银燕 上海市第一妇婴保健院。 雷帕霉素在制备治疗白细胞介素-27低表达子宫内膜癌的药物中的应用。专利申请号201711087886.8 专利申请日期2017-11-08
李明清 常凯凯 李大金 金莉萍 邵珺 刘立兵 复旦大学附属妇产科医院。 白细胞介素抗体在制备子宫内膜异位症药物组合物中的用途。 专利申请号:201610080660.4 专利申请日期:2016-02-04
李明清 李大金 孟玉菡 周文洁 金莉萍 杜美蓉 复旦大学附属妇产科医院。 RANK+巨噬细胞用于制备治疗自然流产保胎药物中的用途。 专利申请号:201610619789.8 专利申请日期:2016-07-31
金莉萍 李明清 汪清 常凯凯 周文洁 商文庆 复旦大学附属妇产科医院。 白细胞介素(IL-22)抗体在制备子宫腺肌症药物中的应用。 专利申请号:201510456481.1 专利申请日期:2015-7-29
参编学术专著 (Published Academic Monograph)
金莉萍:HLA分型,免疫球蛋白替代疗法,免疫性疾病的基因治疗。《临床免疫学》,李大金主编,复旦大学出版社,2005。
金莉萍:MHC在母胎界面中的免疫调节作用;过继性细胞免疫治疗。《生殖免疫学》,李大金主编,复旦大学出版社,2008。
发表论文目录(The Catalog of Published Papers)
#第一/共同第一作者,*通讯作者(# the first / co-first author, * corresponding author)
Wen-Jie Zhou#, Hui-Li Yang#, Jie Mei, Kai-Kai Chang, Han Lu, Zhen-Zhen Lai, Jia-Wei Shi, Xiao-Hui Wang, Ke Wu, Tao Zhang, Jian Wang, Jian-Song Sun, Jiang-Feng Ye, Da-Jin Li, Jian-Yuan Zhao*, Li-Ping Jin*, Ming-Qing Li*. Fructose-1,6-bisphosphate prevents pregnancy loss by inducing decidual COX-2(+) macrophage differentiation. Sci Adv. 2022, 8(8): eabj2488.
Yan Zhao #, Yongbo Zhao #, Kechen Fan, Liping Jin *, Association of History of Spontaneous or Induced Abortion With Subsequent Risk of Gestational Diabetes. JAMA Netw Open. 2022 Mar 1;5(3): e220944.
Yan Zhao #, Kechen Fan #, Yan Zhu #, Yongbo Zhao, Jing Cai, Liping Jin *, Gestational exposure to BDE-209 induces placental injury via the endoplasmic reticulum stress-mediated PERK/ATF4/CHOP signaling pathway. Ecotoxicol Environ Saf. 2022, 233:113307.
Yao Xu#*, Rongxiang Wang#, Zhi Pang#, Zhiyun Wei, Lihua Sun, Sa Li, Guanghua Wang, Yu Liu, Yiwen Zhou, Hongjuan Ye, Liping Jin*, Songguo Xue*. Novel homozygous PADI6 variants in infertile females with early embryonic arrest. Front. Cell Dev. Biol. 2022 Feb accepted. DOI: 10.3389/fcell.2022.819667.
Yao Xu#, Xiuxian Zhu#, Miao Wang, Luyi Cai, Qiulin Ge, Yonglun Fu*, Liping Jin*. The homozygous p.Tyr228Cys variant in CDC20 causes oocyte maturation arrest: an additional evidence supporting causality between CDC20 mutation and female infertility. J Assist Reprod Genet. 2021 Aug;38(8):2219-2222.
Yan Zhao, Yongbo Zhao, Kechen Fan, Liping Jin *, Serum uric acid in early pregnancy and risk of gestational diabetes mellitus: A cohort study of 85,609 pregnant women, Diabetes Metab. 2021, 16;48(3):101293.
Xiao-Hui Wang #, Sha Xu #, Xiang-Yu Zhou #, Rui Zhao, Yan Lin, Jing Cao, Wei-Dong Zang, Hui Tao, Wei Xu, Ming-Qing Li, Shi-Min Zhao, Li-Ping Jin*, Jian-Yuan Zhao*. Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk. Nat Commun. 2021, 12(1): 3428.
Fan Hao#, Lin-Chen Tang #, Jia-Xue Sun, Wen-Xuan Li, Yongbo Zhao, Xiang-Hong Xu*, Liping Jin*. Decreased nitric oxide content mediated by asymmetrical dimethylarginine and protein l-arginine methyltransferase 3 in macrophages induces trophoblast apoptosis: a potential cause of recurrent miscarriage. Hum Reprod, 2021, 36(12): 3049-3061.
Wen-Xuan Li, Xiang-Hong Xu*, Liping Jin*. Regulation of the innate immune cells during pregnancy: An immune checkpoint perspective. J Cell Mol Med. 2021, 25(22): 10362-10375.
Xiang-Hong Xu#, Lin-Chen Tang#, Fan Hao, Li-Ping Jin*. Upregulation of miR-29a suppressed the migration and invasion of trophoblasts by directly targeting LOXL2 in preeclampsia. Journal of Hypertension. 2021 Mar 1. 39(8): 1642-1651.
Yongli Yao, Fan Hao, Lin-Chen Tang, Xiang-Hong Xu*, Liping Jin*. Downregulation of HDAC8 expression decreases CD163 levels and promotes the apoptosis of macrophages by activating the ERK signaling pathway in recurrent spontaneous miscarriage. Molecular Human Reproduction. 2020 Jul 1;26(7):521-531.
Qingliang Zheng#, Tao Duan*, Liping Jin*. Single-cell RNA expression profiling of ACE2 and AXL in the human early maternal-fetal interface. Reproductive and Developmental Medicine. 2020 4(1):7-10.
Yongbo Zhao#, Qingliang Zheng*, and Liping Jin*. The Role of B7 Family Molecules in Maternal–Fetal Immunity. Frontiers in Immunology. 2020 11:458.
Qingliang Zheng#*, Haili Gan#, Fenglian Yang, Yongli Yao, Fan Hao, Ling Hong, Liping Jin*. Cytoplasmic m1A reader YTHDF3 inhibits trophoblast invasion by downregulation of m1A methylated IGF1R. Cell Discovery. 2020 6:12.
Linchen Tang, Xianghong Xu*, Liping Jin*. Molecular characteristics and possible function of innate lymphoid cells under different tissue conditions. Cytokine and Growth Factor Reviews. 2020 52:15-24.
Dongli Cai#, Jiaming Li, Dingfeng Liu, Shanjuan Hong, Qin Qiao, Qinli Sun, Pingping Li, Nanan Lyu, Tiantian Sun, Shan Xie, Li Guo, Ling Ni*, Liping Jin*,Chen Dong*. Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy. Cell Mol Immunol. 2020 17:227-236.
Fan Hao#, Xiangyu Zhou*, and Liping Jin*. Natural Killer Cells: Functional Differences in Recurrent Spontaneous Abortion. Biol Reprod. 2019 19
Fenglian Yang#, Qingliang Zheng*, and Liping Jin*. Dynamic Function and Composition Changs of Immune Cells During Normal and Pathological Pregnancy at the Maternal-Fetal Interface. Frontiers in Immunology. 2019 18:2317-
Yongli Yao#, Xiang-Hong Xu*, and Liping Jin*. Macrophage Polarization in Physiological and Pathological Pregnancy. Frontiers in Immunology. 2019 10:792.
Yuan Zhang#, Ji Zhou#, Ming-qing Li, Jie Xu, Jin-ping Zhang*, Li-ping Jin*. MicroRNA-184 promotes apoptosis of trophoblast cells via targeting WIG1 and induces early spontaneous abortion. Cell Death & Disease. 2019 10:223-231
Xiang-Hong Xu#, Yuanhui Jia, Xinyao Zhou, Dandan Xie, Xiaojie Huang, Linyan Jia, Qian Zhou, Qingliang Zheng, Xiangyu Zhou, Kai Wang*, Li-Ping Jin*. Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating TGF-β/collagen pathway in preeclampsia. Exp Mol Med. 2019 51(2):20
Chao Li#, Lin-Yan Jia, Yong-Sheng Yu, Li-Ping Jin*. Lactic acid induced microRNA-744 enhances motility of SiHa cervical cancer cells through targeting ARHGAP5. Chemico-Biol Interact 2019 298:86-95.
Bing Zhang#, Wen-Jie Zhou#, Chun-Jie Gu, Ke Wu, Hui-Li Yang, Jie Mei, Jia-Jun Yu, Xiao-Fan Hou, Jian-Song Sun, Feng-Yuan Xu, Da-Jin Li, Li-Ping Jin*, Ming-Qing Li*. The ginsenoside PPD exerts anti-endometriosis effects by suppressing estrogen receptor-mediated inhibition of endometrial stromal cell autophagy and NK cell cytotoxicity. Cell Death & Disease 2018 May 1;9(5):574.
Yuan Zhang#, Ying Wang#, Ming-Qing Li, Jie Duan, Deng-Xuan Fan*, Li-Ping Jin*. IL-25 promotes Th2 bias by upregulating IL-4 and IL-10 expression of decidual γδT cells in early pregnancy. Exp Ther Med 2018;15(2): 1855-1862.
Yuan Zhang#, Ying Wang#, Xiao-Hui Wang, Wen-Jie Zhou, Li-Ping-Jin*, Ming-Qing-Li*. Crosstalk between human endometrial stromal cells and decidual NK cells promotes the decidualization in vitro by upregulating IL-25. Mol Med Rep 2018; 17(2):2869-2878.
Dong-Li Cai# and Li-Ping Jin*. Immune Cell Population in Ovarian Tumor Microenvironment. Journal of Cancer. 2017;8(15):2915-2923.
Xiao-Hui Wang#, Wei Liu#, Deng-Xuan Fan, Li-Ping Jin*. IL-33 restricts invasion and adhesion of trophoblast cell line JEG3 by down-regulation of integrinα4β1 and CD62L. Mol Med Rep. 2017 Oct;16(4):3887-3893
Anfei Huang, Si Chen, Yi Yang, Fei Xia, Di Sun, Fulu Dong, Deyu Fang, Sidong Xiong, Liping Jin*, Jinping Zhang*. miR-34a promotes DCs development and inhibits their function on T cell activation by targeting WNT1. Oncotarget. 2017 8(10):17191-17201
Yuan Zhang#, Li-Ping Jin*. Effects of TSLP on Obstetrical and Gynecological Diseases. Am J Reprod Immunol. 2017; 77: e12612.
Han Lu#, Da-Jin Li, Li-Ping Jin*. γδT cells and related diseases. Am J Reprod Immunol. 2016; 75(6):609-18.
Si Chen#, An-Fei Huang#, Huo Chen, Yi Yang, Fei Xia, Li-Ping Jin*, Jin-Ping Zhang*. miR-34a inhibits the apoptosis of MDSCs by suppressing the expression of N-myc. Immunol Cell Biol. 2016; 94(6):563-72
Liu, Li-Bing# ,Xie, Feng# ,Chang, Kai-Kai,Shang, Wen-Qing,Meng, Yu-Han,Yu, Jia-Jun,Li, Hui,Sun, Qian,Yuan, Min-Min,Jin, Li-Ping*,Li, Da-Jin,Li, Ming-Qing*,Chemokine CCL17 induced by hypoxia promotes the proliferation of cervical cancer cell.,American Journal of Cancer Research,2015;5(10)1:3072-3084
Ying Wang#, Xiao-Hui Wang#, Deng-Xuan Fan, Yuan Zhang, Ming-Qing Li, Hai-Xia Wu*, Li-Ping Jin*. PCSK6 regulated by LH inhibits the apoptosis of human granulosa cells via activin A and TGF-β2. J Endocrinol 2014; 222(1):151-160
Fulu Dong#, Yuan Zhang#, Fei Xia, Yi Yang, Si-Dong Xiong, Li-Ping Jin*, Jin-Ping Zhang*. Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. Reproduction 2014;148:33-41
Ying Wang#, Yuan Zhang#, Ming-Qing Li, Deng-Xuan Fan, Xiao-Hui Wang, Da-Jin Li, Li-Ping Jin*. Interleukin-25 induced by human chorionic gonadotrophin promotes the proliferation of decidual stromal cells by activation of JNK and AKT signal pathways. Fertil Steril. 2014; 102(1): 257-263
Ming-Qing Li#, Li-Ping Jin*. Ovarian stimulation for in vitro fertilization alters the protein profile expression in endometrial secretion. Int J Clin Exp Pathol. 2013; 6:1964-1971
Jie Duan#, Xiao-Ping Jiang#, Ming-Qing Li, Deng-Xuan Fan, Ying Wang , Da-Jin Li*, Li-Ping Jin*. Thymic stromal lymphopoietin suppresses the apoptosis of decidual gamma-delta T cells via regulation of the signal transduction and activation of transcription 3/caspase-3 signaling pathway. Am J Reprod Immunol. 2013 70(6):464-471
Ying Wang#, Bing Xu#, Ming-Qing Li, Da-Jin Li*, Li-Ping Jin*. IL-22 secreted by decidual stromal cells and NK cells promotes the survival of human trophoblasts. Int J Clin Exp Pathol. 2013; 15;6(9):1781-1790.
Jie Mei#, Li-Ping Jin#, Ding Ding, Ming-Qing Li, Da-Jin Li, Xiao-Yong Zhu*. Inhibition of IDO1 suppresses cyclooxygenase-2 and matrix metalloproteinase-9 expression and decreases proliferation, adhesion and invasion of endometrial stromal cells. Mol Hum Reprod. 2012;18(10):467-476.
Ying Wang#, Deng-Xuan Fan#, Jie Duan, Ming-Qing Li, Xiao-Yong Zhu*, Li-Ping Jin*. Thymic stromal lymphopoietin downregulates NME1 expression and promotes invasion in human trophoblasts via the activation of STAT3 signaling pathway. Clin. Immunol. 2012; 143 (1):88-95.
Hua-Hua Pu#, Jie Duan, Ying Wang, Deng-Xuan Fana, Da-Jin Li*, Li-Ping Jin*. Thymic stromal lymphopoietin promotes the proliferation of human trophoblasts via phosphorylated STAT3-mediated c-Myc upregulation. Placenta 2012; 33(5): 387-391.
Deng-Xuan Fan#, Jie Duan, Ming-Qing Li, Bin Xu, Da-Jin Li*, Li-Ping Jin*. The decidual gamma-delta T cells up-regulate the biological functions of trophoblasts via IL-10 secretion in early human pregnancy. Clin Immunol. 2011;141: 284-292.
Li-Ping Jin#, Deng-Xuan Fan#, Tai Zhang, Pei-Fen Guo, Da-Jin Li*. The costimulatory signal upregulation is associated with Th1 bias at the maternal–fetal interface in human miscarriage. Am J Reprod Immunol. 2011; 66: 270–278.
Li-Ping Jin#, Deng-Xuan Fan, Da-Jin Li*. Regulation of costimulatory signal pathway in maternal-fetal immune tolerance. Am J Reprod Immunol. 2011; 66: 76-83.
Li-Ping Jin#, Qiao-Ying Chen, Tai Zhang, Pei-Feng Guo, Da-Jin Li*. The CD4+CD25bright regulatory T cells and CTLA-4 expression in peripheral and decidual lymphocytes are down-regulated in human miscarriage. Clin. Immunol. 2009; 133(3):402-410.
Li-Ping Jin#, Yue-Hua Zhou, Ming-Yan Wang, Xiao-Yong Zhu, Da-Jin Li*. Adoptive transfer of paternal antigen-hyporesponsive T cells facilitates a Th2 bia s in peripheral lymphocytes and at materno-fetal interface in abortion-prone mating. Am J Reprod Immunol. 2006; 56(4):258-266.
Li-Ping Jin#, Yue-Hua Zhou, Ming-Yan Wang, Xiao-Yong Zhu, Da-Jin Li*. Blockade of CD80 and CD86 at the time of implantation inhibits maternal rejection of the allogeneic fetus in abortion-prone matings. J Reprod Immunol. 2005; 65(2):133-146.
Li-Ping Jin#, Da-Jin Li*, Jin-Ping Zhang, Ming-Yan Wang, Xiao-Yong Zhu, Ying Zhu, Yi Meng & Min-Min Yuan. Adoptive transfer of paternal antigen-hyporesponsive T cells induces maternal tolerance to the allogeneic fetus in abortion-prone matings. J Immunol. 2004; 173(6):3612-3619.
Li-Ping Jin#, Da-jin Li, Jing-yu Shao. Effect of mifepristone on transforming growth factor –beta and its receptor transcription in decidua,villi and serum tumor necrosis factor –alpha level of early human gestation. Reproduction & Contraception. 2004; 15 (1):33-38.
Hui Li#, Yu-Han Meng, Wen-Qing Shang, Li-Bing Liu, Xuan Chen, Min-Min Yuan, Li-Ping Jin, Ming-Qing Li*, Da-Jin Li*. Chemokine CCL24 promotes the growth and invasiveness of trophoblasts through ERK1/2 and PI3K signaling pathways in human early pregnancy. Reproduction. 2015; 150(5):417-427.
Jie Mei#, Xiao-Yong Zhu#, Li-Ping Jin, Zhong-Liang Duan, Da-Jin Li*, Ming-Qing Li*. Estrogen promotes the survival of human secretory phase endometrial stromal cells via CXCL12/CXCR4 up-regulation-mediated autophagy inhibition. Hum Reprod. 2015; 30(7):1677-1689.
Min-Min Yuan#, Mei-Rong Du, Ming-Yan Wang, Zhong-Liang Duan, Yi Meng, Li-Ping Jin, Ming-Qing Li*, Da-Jin Li*. Combination analysis of CD4+CD25+CD127- regulatory T cells with MLC-BE and BE-Ab2: an efficient evaluation of the therapy of paternal lymphocyte induced immunization in unexplained recurrent spontaneous abortion patients. Int J Clin Exp Pathol. 2015; 8(4):4022-4032.
Wen-Ting Hu#, Li-Li Huang#, Ming-Qing Li, Li-Ping Jin, Da-Jin Li, Xiao-Yong Zhu*. Decidual stromal cells-derived IL-33 contributes to Th2 bias and inhibits decidual NK cell cytotoxicity through NF-κB signaling in human early pregnancy. J Reprod Immunol. 2015; 109:52-65.
Ming-Qing Li#, Yun Wang#, Kai-Kai Chang#, Yu-Han Meng, Li-Bing Liu, Jie Mei, Ying Wang, Xiao-Qiu Wang, Li-Ping Jin, Da-Jin Li*. CD4+Foxp3+ regulatory T cell differentiation mediated by endometrial stromal cell-derived TECK promotes the growth and invasion of endometriotic lesion. Cell Death Dis. 2014; 5:e1436
Qing Wang#, Li Wang, Jun Shao, Yan Wang, Li-Ping Jin, Da-Jin Li, Ming-Qing Li*. L-22 enhances the invasiveness of endometrial stromal cells of adenomyosis in an autocrine manner. Int J Clin Exp Pathol. 2014; 7(9): 5762-5771.
Jie Mei#, Xue-Xin Xie#, Ming-Qing Li, Chun-Yan Wei, Li-Ping Jin, Da-Jin Li, Xiao-Yong Zhu*. Indoleamine 2,3-dioxygenase-1 (IDO1) in human endometrial stromal cells induces macrophage tolerance through interleukin-33 in the progress of endometriosis. Int J Clin Exp Pathol. 2014; 7(6): 2743-2757.
Chuan-Ling Tang#, Jing Liang, Jin-Feng Qian, Li-Ping Jin, Mei-Rong Du, Ming-Qing Li, Da-Jin Li*. Opposing role of JNK-p38 kinase and ERK1/2 in hydrogen peroxide-inducedoxidative damage of human trophoblast-like JEG-3 cells. Int J Clin Exp Pathol. 2014; 7(3):959-968.
Wen-Ting Hu#, Ming-Qing Li, Wei Liu, Li-Ping Jin, Da-Jin Li, Xiao-Yong Zhu*. IL-33 enhances proliferation and invasiveness of decidual stromal cells by up-regulation of CCL2/CCR2 via NF-κB and ERK1/2 signaling. Mol Hum Reprod. 2014; 20(4):358-372.
Kai-Kai Chang#, Li-Bing Liu#, Li-Ping Jin, Yu-Han Meng, Jun Shao, Ying Wang, Jie Mei, Ming-Qing Li*, Da-Jin Li*. NME1 suppression of endometrial stromal cells promotes angiogenesis in the endometriotic milieu via stimulating the secretion of IL-8 and VEGF. Int J Clin Exp Pathol. 2013; 6(10):2030-2038.
Hui Li#, Yuan-Hua Huang#, Ming-Qing Li, Yu-Han Meng, Xuan Chen, Jun Shao, Chuan-Ling Tang, Mei-Rong Du, Li-Ping Jin, Da-Jin Li*. Trophoblasts-derived chemokine CCL24 promotes the proliferation, growth and apoptosis of decidual stromal cells in human early pregnancy. Int J Clin Exp Pathol. 2013; 6(6): 1028–1037.
Jie Mei#, Ming-Qing Li#, Ding Ding, Da-Jin Li, Li-Ping Jin, Wei-Guo Hu*, Xiao-Yong Zhu*, Indoleamine 2,3-dioxygenase-1 (IDO1) enhances survival and invasiveness of endometrial stromal cells via the activation of JNK signaling pathway. Int J Clin Exp Pathol. 2013; 6(3): 431–444.
Song-Cun Wang#, Min Yu#, Yan-Hong Li, Hai-Lan Piao, Chuan-Lin Tang, Chan Sun, Rui Zhu, Ming Qing Li, Li-Ping Jin, Da-Jin Li*, Mei-Rong Du*. Cyclosporin A promotes proliferating cell nuclear antigen expression and migration of human cytotrophoblast cells via the mitgen-activated protein kinase-3/1-mediated nuclear factor-κB signaling pathways. Int J Clin Exp Pathol. 2013; 6(10): 1999–2010.
Yu-Han Meng#, Hui Li, Xuan Chen, Li-Bing Liu, Jun Shao, Kai-Kai Chang, Mei-Rong Du, Li-Ping Jin, Ming-Qing Li*, Da-Jin Li*. RANKL promotes the growth of decidual stromal cells in an autocrine manner via CCL2/CCR2 interaction in human early pregnancy. Placenta. 2013; 34(8):663-671.
Ming-Qing Li#, Xue-Zhen Luo#, Yu-Han Meng, Jie Mei, Xiao-Yong Zhu, Li-Ping Jin, Da-Jin Li*. CXCL8 enhances proliferation and growth and reduces apoptosis in endometrial stromal cells in an autocrine manner via a CXCR1-triggered PTEN/AKT signal pathway. Hum Reprod. 2012; 27:2107-2116.
Pei-Feng Guo#, Mei-Rong Du#, Hai-Xia Wu#, Yi Lin, Li-Ping Jin, Da-Jin Li*: Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory TH2 bias in the decidua during early gestation in humans. Blood. 2010;116:2061-2069.
Hai-Xia Wu#, Pei-Feng Guo#, Li-Ping Jin, Shan-shan Liang, Da-Jin Li*. Functional regulation of thymic stromal lymphopoietin on proliferation and invasion of trophoblasts in human first-trimester pregnancy. Hum Reprod. 2010;25:1146-1152.
Xia Wu#, Li-Ping Jin, Min-min Yuan, Ying Zhu, Yi Meng, Ming-yan Wang, Da-Jin Li*. Human first-trimester trophoblast cells recruit CD56brightCD16- NK cells into decidua by way of expressing and secreting of CXCL12/SDF-1. J Immunol. 2005; 175(1):61-68.
Xiao-Yong Zhu#, Yue-Hua Zhou, Ming-Yan Wang, Li-Ping Jin, Min-Min Yuan, Da-Jin Li*. Blockade of CD86 signaling facilitates a Th2 Bias at the materno-fetal interface and expands peripheral CD4+CD25+ regulatory T cells to rescue the abortion-prone fetuses. Biol Reprod. 2005;72(2):338-45.