前列腺炎癌转化的临床和基础研究
(Clinical and basic researches on transformation from prostatitis and prostate cancer)
前列腺炎与性功能障碍的机制研究和治疗探索
(Mechanism study and treatment exploration of prostatitis-related sexual dysfunction)
尿路结石微创治疗的并发症防治和器械创新，尤其是脓毒血症和输尿管狭窄的预防、治疗以及机制研究
(Complications prevention and treatment on minimally invasive treatment of urolithiasis and the innovation of related surgical instruments, especially the prevention, treatment and mechanism study of urosepsis and ureteral stricture)
主持国家自然科学基金面上项目1项、上海市科委课题1项、上海市卫健委课题1项和校院级课题3项，以主要完成人参与各级课题10余项。主编科普论著3部，参编论著10余部，以第一作者或通讯作者发表论文35篇，其中SCI收录16篇。以主要完成人荣获教育部科技进步一等奖1项，上海医学二等奖1项，上海科技进步二等奖1项，中华医学三等奖1项，华夏医学三等奖2项，上海科普教育创新奖二等奖1项，上海市优秀科普图书1项，以及上海市卫生健康行业优秀团干部和优秀团员等大量荣誉称号。
Wang presided one general project of the National Natural Science Foundation of China, one project of the Shanghai Municipal Science and Technology Commission, one project of the Shanghai Municipal Health Commission, and 3 projects of Tongji University and Shanghai Tenth People’s Hospital, and participated in more than 10 projects as main participants. Wang edited 3 popular science books and participated in the edition of more than 10 books. As the first author or corresponding author, Wang have published 35 papers included 16 SCI papers. As the main contributor, Wang won first prize for scientific and technological progress Award from the Ministry of Education, second prize for Shanghai Medicine Award, second prize of the Shanghai Medical Science and Technology Award, third prize for Chinese Medicine Award, third prize for Huaxia Medicine Award, second prize for Shanghai Science Popularization Education Innovation Award, Shanghai excellent science popularization book Award, and a large number of honorary titles such as excellent youth league cadres and members in Shanghai health industry.
主持科研课题 (presided scientific research projects)：
1.慢性前列腺炎介导背根神经节CD36高表达诱发勃起功能障碍的机制研究
Chronic prostatitis mediates high CD36 expression in lumbosacral dorsal root ganglion to induce erectile dysfunction
2. CRISPR/Cas敲除SLC7A9基因诱导B型胱氨酸尿症大鼠模型中miR-29调控Fibrinogen表达导致肾小管上皮转化及肾纤维化的机制研究
Mechanism of miR-29 regulates Fibrinogen expression leading to tubular epithelial transformation and renal fibrosis in B-type cystinuria rat model induced by SLC7A9 gene knockout with CRISPR/Cas.
3. 炎症环境通过NF-KB信号通路促进前列腺癌发生的初步研究
Preliminary study on the promotion of NF-KB signaling pathway on prostate cancer development in inflammatory environment
4. 炎症介质调控长链非编码RNA促进前列腺癌发生机制的研究
Study on the mechanism of long non-coding RNA mediated by inflammatory mediators promotes prostate cancer development
代表性论文 (Representative papers）：
1. A comparative study of thulium laser resection of the prostate and bipolar transurethral plasmakinetic prostatectomy for treating benign prostatic hyperplasia. BJU Int. 2013 Apr; 111(4): 633-7.
2. Impacts of Histological Prostatitis on Sexual Function and Lower Urinary Tract Symptoms in Patients With Benign Prostatic Hyperplasia. Urology. 2013 Nov; 82(5): 1094-7.
3. Differential research of inflammatory and related mediators in BPH, histological prostatitis and PCa. Andrologia. 2018 Feb 14.
4. Analysis of the clinical effect and long-term follow-up results of retroperitoneal laparoscopic ureterolithotomy in the treatment of complicated upper ureteral calculi (report of 206 cases followed for 10 years). Int Urol Nephrol 2019 Nov; 51(11): 1955-1960.
5. Structural and functional abnormalities of penile cavernous endothelial cells result in erectile dysfunction at experimental autoimmune prostatitis rat. J Inflamm (Lond). 2019 Jul 25; 16: 20.
6. Corpus cavernosum smooth muscle cell dysfunction and phenotype transformation are related to erectile dysfunction in prostatitis rats with chronic prostatitis/chronic pelvic pain syndrome. J Inflamm (Lond). J Inflamm (Lond). 2020 Jan 6;17: 2.
7. Survival nomogram for patients with bone metastatic renal cell carcinoma: A population-based study. Int Braz J Urol 2021 Mar-Apr; 47(2):333-349.
8. Inflammation induced by lipopolysaccharide advanced androgen receptor expression and epithelial-mesenchymal transition progress in prostatitis and prostate cancer. Transl Androl Urol 2021.
代表性专著 (Representative books)：
前列腺增生与前列腺癌医患问答，第二军医大学出版社，上海，2015年12月
名医讲堂前列腺疾病300问，上海交通大学出版社，上海，2018年3月
名医讲堂尿路结石200问，上海交通大学出版社，上海，2021年5月
