植物功能活性成分对皮肤健康的影响，皮肤肿瘤的发病机制和临床干预

Effects of plant functional active ingredients on skin health, pathogenesis and clinical intervention of skin tumors

2021.8～至今：上海市皮肤病医院，病理科，副研究员

2020.4～2021.4：上海交通大学，联合培养博士

2018.9～2021.6：河南农业大学，博士

2021.8 ~ Present: Associate Researcher, Department of Pathology, Shanghai Skin Disease Hospital

2020.4 ~ 2021.4: Shanghai Jiao Tong University, joint doctoral training

2018.9 ~ 2021.6: Henan Agricultural University, Ph.D

以第一作者在Ecotoxicology and environmental safety、Toxins和 Journal of applied toxicology等杂志发表SCI论文10篇，累计影响因子达47.83；同时发表EI论文1篇、中文核心期刊4篇。作为项目负责人先后主持国家自然科学基金青年项目1项、上海市“科技创新行动计划”自然科学基金面上项目1项，上海市皮肤病医院学术骨干项目1项，参与多项国自然面上项目。

As the first author, I have published 10 SCI in the Journals such as Ecotoxicology and environmental safety, Toxins and Journal of applied toxicology, with a cumulative impact factor of 47.83. At the same time, he published 1 study in EI paper and 4 studies in Chinese core journals. As the project leader, he has obtained 1 National Natural Science Foundation Youth project, 1 Shanghai Science and Technology Innovation Action Plan Natural Science Foundation project, 1 academic backbone project of Shanghai Skin Disease Hospital, and participated in a number of National Natural Science Foundation projects.

发表文献：

[1] Xiaoxiang Xu, Juan Chang, Ping Wang, et al. Combination of glycyrrhizic acid and compound probiotics alleviates deoxynivalenol-induced damage to weaned piglets. Ecotoxicology and environmental safety, 2023 年 5 月，IF=6.80 (JCR 1 区);

[2] Xiaoxiang Xu, Ningyuan Xi, Shejia Chen, et al. Deoxynivalenol exposure induces oxidative stress and apoptosis in human keratinocytes via PI3K/Akt and MAPK signaling pathway. Environmental Toxicology. 2023 年 8 月，IF=4.50 (JCR 2 区);

[3] Xiaoxiang Xu, Juan Chang, Ping Wang, et al. Glycyrrhinic acid and probiotics alleviate deoxynivalenol-induced cytotoxicity in intestinal epithelial cells. AMB Express, 2023 年 5 月，IF=3.70 (JCR 2 区);

[4] Xiaoxiang Xu, Juan Chang, Ping Wang, et al. Glycyrrhizic acid and compound probiotics supplementation alters the intestinal transcriptome and microbiome of weaned piglets exposed to deoxynivalenol. Toxins, 2022 年 12 月, IF=4.20 (JCR 1 区);

[5] Xiaoxiang Xu, Juan Chang, Ping Wang, et al. Effect of chlorogenic acid on alleviating inflammation and apoptosis of IPEC-J2 cells induced by deoxyniyalenol. Ecotoxicology and environmental safety, 2020 年 9 月，IF=6.29 (JCR 1 区);

[6] Xiaoxiang Xu, Guorong Yan, Juan Chang, et al. Comparative transcriptome analysis reveals protective mechanism of glycyrrhinic acid for deoxynivalenol-induced inflammation and apoptosis in IPEC-J2 cells. Oxidative medicine and cellular longevity, 2020 年 10 月，IF=6.542 (JCR 2 区);

[7] Xiaoxiang Xu, Yingjia Wei, Mian Khaqan Shah, et al. Effects of compound active peptides on protecting liver and intestinal epithelial cells from damages and preventing hyperglycemia. Oxidative medicine and cellular longevity, 2020 年 4 月，IF=6.542 (JCR 2 区);

[8] Xiaoxiang Xu, Guorong Yan, Juan Chang, et al. Astilbin ameliorates deoxynivalenol-induced oxidative stress and apoptosis in intestinal porcine epithelial cells (IPEC-J2). Journal of applied toxicology, 2020 年 4 月，IF=3.444 (JCR 2 区);

[9] Xiaoxiang Xu, Canyu Yang, Juan Chang, et al. Dietary Supplementation with compound probiotics and berberine alters piglet production performance and fecal microbiota. Animals, 2020 年 3 月，IF=2.75 (JCR 1 区);

[10] Xiaoxiang Xu, Zhongping Yin, Jiguang Chen, et al. De Novo Transcriptome assembly and annotation of the leaves and callus of Cyclocarya paliurus (Bata1) Iljinskaja. Plos one，2016 年 8 月，IF=3.059 (JCR 2 区);

[11] 许小向等，青钱柳鲨烯合成酶(CpSS)全长基因的克隆、分析与表达，中国食品学报(EI)，2020;

[12] 许小向等，火炬松松针多糖提取工艺及其抗氧化性研究，林产化学与工业，2016;

[13] 许小向等，松针多糖微波提取工艺及抗氧化性研究，食品工业科技，2015;

[14] 许小向等，松针多糖的提取工艺及稳定性研究，食品科技，2015;

[15] 许小向等，红巧梅花色苷树脂静态纯化工艺研究，江西农业大学学报，2015。