Fundings:
1. 国家自然科学基金面上项目,81770732,JNK通过介导Bcl-2磷酸化调控尿毒症肠上皮细胞MPTP的作用及机制研究,2018/01-2021/12,56万,在研,主持。
2. 上海市崇明科委面上项目,CKY2017-19, JNK磷酸化调控尿毒症肠上皮细胞凋亡的作用及机制研究,2017/03-2019/02,3万,已结题,主持。
3.上海市卫生和计划生育委员会项目,201440478,氯化锂抑制肾小球足细胞线粒体损伤的机制研究,2015/01-2017/12,3万元,已结题,主持。
4.国家自然科学基金青年项目,81101414,基质Gla蛋白通过抑制TGF-beta信号通路在百草枯中毒肾损伤中起保护作用,2012/01-2014/12,22万,已结题,主持。
5.美高梅2009
年美高梅青年优秀人才培养行动计划,2009KJ024,20009/12-2011/11,2万,已结题,主持。
6.国际肾脏病学会(ISN Fellow)至美国布朗大学,2011/12-2013/12,2014年被授予ISN Fellowship,4.4万美元,已结题,主持。
7.国际肾脏病学会(travel grant),2015年,南非开普敦 “2015年世界肾脏病大会(WCN)”,1250美元,已执行。
Papers:
[1]
Wang Z, Bao H, Ge Y, Zhuang S, Peng A, Gong R*. Pharmacological
targeting of GSK3β confers protection against podocytopathy and proteinuria by
desensitizing mitochondrial permeability transition. British journal of
pharmacology.2015 Feb;172(3):895-909.
[2]
Wang Z, Ge Y, Bao H, Dworkin L, Peng A, Gong R*. Redox-sensitive
glycogen synthase kinase 3 β -directed control of mitochondrial permeability
transition: rheostatic regulation of acute kidney injury[J]. Free Radical
Biology and Medicine, 2013, 65: 849-858.
[3] Zhen Wang,
Chao Yu, Bing-qing Deng,and Xin-hua Li. The prognostic value of oxidative stress and
inflammation in Chinese hemodialysis patients. Renal Failure.2017
Nov;39(1):54-58. doi: 10.1080/0886022X.2016.1244078.Epub 2016 Oct 21.
[4]
Wang Z, Yu C, Zhou LN, Chen X. Effects of Tripterygium wilfordii
Induction Therapy to IgA Nephropathy Patients with Heavy Proteinuria. Biol
Pharm Bull. 2017 Nov 1;40(11):1833-1838.
[5]
Yu C, Tan S, Wang Z (Co-corresponding Author), Deng B,Li J, Wang Q, Zhou
C, Kang X, Yu Z, Zhuang S. Chronic Kidney Disease Elicits an Intestinal
Inflammation Resulting in Intestinal Dysmotility Associated with the Activation
of Inducible Nitric Oxide Synthesis in Rat. Digestion 2018;97:205–211.
[6]Yu
C, Wang Z(Corresponding Author), Tan S, Wang Q, Zhou
C, Kang X, Zhao S, Liu S, Fu H,Yu Z, Peng A. Chronic Kidney Disease Induced
Intestinal Mucosal Barrier Damage Associated with Intestinal Oxidative Stress
Injury. Gastroenterol Res Pract.2016;2016:6720575. PMID: 27493661 DOI:
10.1155/2016/6720575. Epub 2016 Jul14.
[7]Yu C, Tan S, Zhou
C, Zhu C, Kang X, Liu S, Zhao S, Fan S, Yu Z, Peng A, Wang Z(Corresponding
Author). Berberine Reduces Uremia-associated Intestinal Mucosal
Barrier Damage. Biol Pharm Bull. 2016 Aug 9. [Epub ahead of print] PMID: 27506986
DOI:10.1248/bpb.b16-00280
[8]
Wang Z, Tang Z, Zhang HT, Hu WX, Liu ZH, Li LS. Clinicopathological
characteristics of familial SLE patients with lupus nephritis.Lupus. 2009
Mar;18(3):243-8.