曾任上海交通大学海科院助理研究员,复旦大学上海美高梅分子遗传学副教授;先后在美国亚历桑那大学和纽约西奈山美高梅从事肌球蛋白磷酸化酶生物化学和钾离子通道分子遗传学研究,曾任西奈山美高梅儿科系研究员,从事发育早期细胞分化方面的研究;回国后创建59599aa美高梅医学遗传学教研室,并任创建主任。目前担任59599aa美高梅教授委员会主任;59599aa美高梅转化医学研究管理办公室主任;心律失常教育部重点实验室常务副主任;美国人类遗传学会(ASHG)会员;国际干细胞研究学会(ISSCR)会员;美洲华人遗传学会会员;中国药理学会药物基因组学专业委员会委员。
课题组代表性论文
1.Impact of miR-26b on cardiomyocyte differentiation in P19 cells through regulating canonical/non-canonical Wnt signalling. Wang D, Liu C, Wang Y, Wang W, Wang K, Wu X, Li Z, Zhao C, Li L, Peng L. Cell Prolif. 2017 Dec;50(6).doi: 10.1111/cpr.12371. Epub 2017 Aug 15.
2.Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells. Wang D, Liu C, Li Z, Wang Y, Wang W, Wu X, Wang K, Miao W, Li L, Peng L. J Cell Biochem. 2017 Dec;118(12):4460-4467.
3.Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2. Miao W, Wu X, Wang K, Wang W, Wang Y, Li Z, Liu J, Li L, Peng L. Int J Mol Sci. 2016 Oct 10;17(10). pii: E1696.
4.Liu JJ, Zhao CM, Li ZG, Wang YM, Miao W, Wu XJ, Wang WJ, Liu C, Wang D, Wang K, Li L, Peng LY.miR-218 Involvement in Cardiomyocyte Hypertrophy Is Likely through Targeting REST. Int J Mol Sci. 2016 May 31;17(6). pii: E848. doi: .3390/ijms17060848.