蒋晓燕，59599aa美高梅心律失常教育部重点实验室教授，博士生导师。为如皋衰老纵向队列的核心建设者（Rugao Longevity and Ageing Study, RuLAS）Co-PI，建立队列数据库，建立多学科(各器官、系统、社会心理)表型、基因组、代谢组、宏基因组等多组学数据库。研究方向：心血管与代谢性疾病分子和遗传流行病学。长期从事心血管代谢性疾病及衰弱的分子和遗传流行病学研究，并有多年的多基因病与药物遗传学咨询、心血管药理学及病理生理学研究教学经历。主持国家自然科学基金面上项目、国家自然科学基金青年基金、国家教育部博士点新教师基金、上海市自然科学基金、中央高校基本科研业务费专项基金等项目。为国家重点研发计划“主动健康和老龄化科技应对”专项“老年衰弱快速筛查评估量表的研发与建立”任务责任人。发表SCI论文50多篇，其中以通讯或第一作者（含并列）名义发表SCI论文26篇。获济南市科技进步二等奖（2015，排名第二）。是国家自然科学基金及教育部博士学位论文评审专家以及J Nutr Health Aging、Frontiers in Public Health、Molecular Biology Reports、Psychiatry Research等国际SCI期刊的审稿人。

Xiao-Yan Jiang, Ph.D., Professor (Ph.D.Supervisor) of the key laboratory of arrhythmias of ministry of Education of China and the assistant director of the department of pathology and pathophysiology. Research field: molecular epidemiology in cardiology and metabolic disease. Reviewer of the National Natural Science Foundation, the Doctoral Dissertation of the Ministry of Education, and the SCI journals (Nutr Health Aging, Frontiers in Public Health, Molecular Biology Reports, Psychiatry Research). Grants: the National Key R&D Program of China；the National Natural Science Foundation; the Research Fund for the Doctoral Program of Higher Education of China; the Shanghai Municipal Natural Science Foundation; the Fundamental Research Funds for the Central Universities. Awards: the Second Prize of Jinan Science and Technology Progress Award (2015, rank second).

为如皋衰老纵向队列的核心建设者（Rugao Longevity and Ageing Study, RuLAS）Co-PI。

1.H Zhang#, M Sun#, Z Hu, Y Cao, M Hao, Y Li, L Jin, X Sun, X Wang, X Jiang*. Association of Arterial Stiffness with Functional Disability and Mobility Limitation: The Rugao Longitudinal Ageing Study. J Nutr Health Aging. 2022; Online ahead of print. (corresponding author)

2.Yuan JL#, Zhao RX#, Ma YJ, Li XD, Zhou XM, Wang XF, Jiang XY*, Li SJ*. Prevalence/potential risk factors for motoric cognitive risk and its relationship to falls in Chinese elderly people: A cross-sectional study. Eur J Neurol. 2021 Aug;28(8):2680-2687. doi: 10.1111/ene.14884. （co-corresponding author)

3.Ma Y#, Li X#, Pan Y, Zhao R, Wang X, Jiang X*, Li S*.Cognitive frailty and falls in Chinese older people：a population-based longitudinal study. Eur J Neurol. 2021 Feb; 28(2):381-388. doi: 10.1111/ene.14572.（co-corresponding author)

4.Ma Y#, Li X#, Pan Y, Zhao R, Wang X, Jiang X*, Li S*. Cognitive frailty predicting death and disability in Chinese elderly. Neurol Res. 2021 Oct;43(10):815-822. doi: 10.1080/01616412.2021.1939235. （co-corresponding author)

5.Guo JH#, Shi JM#, Shi GP, Wang Y, Chu XF, Wang ZD, Yao S, Sun XH, Wang XF, Zhu YS*, Jiang XY*. Association Study of Mitochondrial DNA Haplogroup D and C5178A Polymorphisms with Chronic Kidney Disease. Genet Test Mol Biomarkers. 2021 Aug;25(8):546-550. doi: 10.1089/gtmb.2020.0306. （co-corresponding author）

6.Chen Z#, Jiang X#, Shi G, Wang Y, Chu X, Wang Z, Guo J, Zhu Y, Chen J, Wang X, Bao Z*. Social frailty and longitudinal risk of depressive symptoms in a Chinese population: the Rugao Longevity and Aging Study. Psychogeriatrics. 2021 Jul;21(4):483-490. doi: 10.1111/psyg.12696. Epub 2021 May 6. （co-first author）

7.Sun XH#, Ma T#, Yao S, Chen ZK, Xu WD, Jiang XY*, Wang XF*. Associations of sleep quality and sleep duration with frailty and pre-frailty in an elderly population Rugao longevity and ageing study. BMC Geriatr. 2020 Jan 6;20(1):9. doi: 10.1186/s12877-019-1407-5. （co-corresponding author)

8.Ma T#, Sun XH#, Yao S, Chen ZK, Zhang JF, Xu WD, Jiang XY*, Wang XF*. Genetic Variants of Homocysteine Metabolism, Homocysteine, and Frailty - Rugao Longevity and Ageing Study.J Nutr Health Aging. 2020;24(2):198-204. doi: 10.1007/s12603-019-1304-9. （co-corresponding author)

9.Li YX#, Jiang XY#, Stone C, Ma YJ, Liu Q, Hu ZH, Li XD, Wang XF, Li SJ. A new physical-cognitive scale for assessment of frailty in Chinese Han elderly. Neurol Res. 2019 Aug;41(8):728-733. doi: 10.1080/01616412.2019.1609164. Epub 2019 Apr 28. （co-first author）

10.Shi GP#, Ma T#, Zhu YS, Wang ZD, Chu XF, Wang Y, Chen ZK, Xu WD, Wang XF, Guo JH, Jiang XY*. Frailty phenotype, frailty index and risk of mortality in Chinese elderly population- Rugao longevity and ageing study. Arch Gerontol Geriatr. 2019 Jan - Feb;80:115-119. doi: 10.1016/j.archger.2018.11.001. Epub 2018 Nov 6.（co-corresponding author）

11.Ma T #, Cai J#, Zhu Y, Chu X, Wang Y, Shi G, Wang Z, Yao S, Wang X*, Jiang X*. Association between a frailty index based on common laboratory tests and QTc prolongation in older adults: the rugao longevity and Ageing study. Clin Interv Aging. 2018;13:797-804. eCollection 2018. （co-corresponding author）

12.Zheng HX#, Li L#, Jiang XY#, Yan S, Qin Z, Wang X, Jin L. MtDNA genomes reveal a relaxation of selective constraints in low-BMI individuals in a Uyghur population. Hum Genet (2017) 136:1353–1362. （co-first author）

13.Wang Y#, Ma T#, Zhu YS, Chu XF, Yao S, Wang HF, Cai J, Wang XF*, Jiang XY*. The KSR2-rs7973260 Polymorphism is Associated with Metabolic Phenotypes, but Not Psychological Phenotypes, in Chinese Elders. Genet Test Mol Biomarkers. 2017 Jul;21(7):416-421. （co-corresponding author）

14.Zhi T#, Wang Q#, Liu Z#, Zhu Y, Wang Y, Shi R, Wang Z, Chu X, Wang X, Jiang X*. Body mass index, waist circumference and waist-hip ratio are associated with depressive symptoms in older Chinese women: results from the Rugao Longevity and Ageing Study (RuLAS). Aging Ment Health. 2017 May;21(5):518-523. doi: 10.1080/13607863.2015.1124837. Epub 2015 Dec 21. (corresponding author)

15.Hao M#, Zhang H#, Hu Z, Jiang X, Song Q, Wang X, Wang J, Liu Z*, Wang X*, Li Y*, Jin L*. Phenotype correlations reveal the relationships of physiological systems underlying human ageing. Aging Cell. 2021 Dec;20(12):e13519.

16.Zhang H#, Zhu Y#, Hao M, Wang J, Wang Z, Chu X, Bao Z, Jiang X, Shi G*, Wang X*. The modified Healthy Aging Index is Associated with Mortality and Disability: The Rugao Longevity and Ageing Study. Gerontology. 2021;67(5):572-580.

17.Zhang H#, Zhu Y#, Gong W, Sun X, Jiang X, Wang J, Jin L, Xu X, Luo D*, Wang X*. Plasma Homocysteine and Macular Thickness in Older Adults-the Rugao Longevity and Aging Study. Eye (Lond). 2021. Online ahead of print.

18.Zhang H#, Li Y#, Hao M, Jiang X, Wang J, Jin L, Bao Z*, Wang X*. Kidney function decline is associated with an accelerated increase in plasma homocysteine in older adults: a longitudinal study. Br J Nutr. 2021, 24:1-7.

19.Chu X#, Zhang N#, Shi G, Wang Y, Wang Z, Guo J, Jiang X, Jin L, Wang X*, Zhu Y*. Frailty and Incident Depressive Symptoms in a Chinese Sample: The Rugao Longevity and Ageing Study. Psychogeriatrics. 2020;20(5):691-698.

20.Wang Z#, Yao S#, Shi G, Wang Y, Shi J, Guo J, Zhu Y, Jiang X, Chu X*, Wang X*.Frailty index is associated with increased risk of elevated BNP in an elderly population: the Rugao Longevity and Ageing Study. Aging Clin Exp Res. 2020;32(2):305-311.

21.Yao S, Zhu Y , Shi G, Guo J, Wang Z, Chu X, Jiang X, Jin L*, Wang X*. Associations of TNF-α -308 G>A and TNF-β 252 A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. J Nutr Health Aging. 2020;24(3):358-363.

22.Zhang N#, Shi GP#, Wang Y, Chu XF, Wang ZD, Shi JM, Guo JH, Wang YC, Yao S, Jiang XY, Zhu YS*, Wang XF*. Depressive symptoms are associated with incident frailty in a Chinese population- the Rugao Longevity and Ageing Study. Aging Clin Exp Res. 2020;32(11):2297-2302.

23.Yao S#, Guo J#, Shi G, Zhu Y, Wang Y, Chu X, Jiang X, Jin L, Wang Z*, Wang X*. Association Of BNP with frailty in elderly population: Rugao Longevity and Ageing Study. J Nutr Health Aging. 2019;23(1):73-78.

24.Ma T, Lu D, Zhu Y, Chu X, Wang Y, Shi G, Wang Z, Yu L, Jiang X, Wang X*.ACTN3 genotype and physical function and frailty in an elderly Chinese population: the Rugao Longevity and Ageing Study. Age Ageing. 2018;47(3):416-422.

25.Liu Q#, Li Y, Hu Z, Jiang X, Li S*, Wang X*. Comparing associations of different metabolic syndrome definitions with ischemic stroke in Chinese elderly population. Eur J Intern Med. 2018,47:75-81.

26.Liu Q, Li Y, Hu Z, Jiang X, Li S*, Wang X*. Reduced estimated glomerular filtration rate is associated with depressive symptoms in elder Chinese: A population-based cross-sectional study. Neurosci Lett. 2018;666:127-132.

27.Ma T#, Shi G#, Zhu Y, Wang Y, Chu X, Jiang X, Liu Z, Cai J, Wang H, Jin L, Wang Z*, Wang X*. Sleep disturbances and risk of falls in an old Chinese population-Rugao Longevity and Ageing Study. Arch Gerontol Geriatr. 2017,12;73:8-14.

28.Liu Q#, Li Y, Hu Z, Jiang X, Li S*, Wang X*. Reduced estimated glomerular filtration rate is associated with depressive symptoms in elder Chinese: a population-based cross-sectional study. Neurosci Lett. 2017;666:127-132.