探究宿主的抗结核感染免疫保护机制Protective mechanisms of anti-TB immunity in humans；

研发新型的针对结核病尤其是耐多药结核病的免疫治疗策略Immune intervention for potential adjunctive treatment of TB and drug-resistant TB.

研究员，上海市肺科医院，美高梅高等研究院Professor, Shanghai pulmonary hospital, Institute of advanced study of Tongji University；

常务委员，中国防痨协会结核病转化医学专业分会Executive committee member, Translational Medicine Branch of China Anti-tuberculosis Associatio；

委员，中华医学会结核病学分会结核病基础研究专业委员会Committee member, Branch of basic tuberculosis research, Chinese medical association

目前主要进行人和灵长类动物的抗结核免疫机制及免疫治疗研究。已经在Proc Natl Acad Sci USA, Angew Chem Int Ed Engl, Immunol Rev, Emerg Microbes Infect.，J Infect Dis., Cell Mol Immunol. J Immunol., Front Immunol. Mater Sci Eng C Mater Biol Appl, Eur J Immunol.等主流学术杂志发表第一或通讯作者论文40余篇, 申请专利6项，其中2项获得授权。获得包括国家重点研发计划，美国NIH基金，国家自然科学基金，传染病重大专项，中科院基金，上海市科委项目及国家和上海市博士后基金等20余项资助。

Our research interesting mainly focuses on the protective mechanisms of anti-TB immunity in humans and nonhuman primates. We have published more than 40 papers in major career journals, such as PNAS, J Infect Dis., J Immunol., Eur J Immunol and so on. I have been awarded as PI more than 20 grants.