研究成果共发表SCI论文15篇，总影响因子89.2，其中以第一或通讯作者在ATVB、Cancer letters、British Journal of Pharmacology等国际高水平期刊发表SCI论文7篇。作为项目负责人承担国自然面上项目、青年项目等国家级项目，中国博士后面上项目、上海市科委项目等省部级项目，获美国心脏学会年会青年科学家旅行奖等国际及国内科研奖励。
【主持省部级及以上科研项目】
1）国家自然科学基金面上项目（82270414）
2）上海市科委生物医药科技支撑专项项目（21S11902900）
3）中国博士后科学基金面上项目（2018M642090）
4）国家自然科学基金青年科学基金项目（81700431）
【代表性文章】（#第一作者，*通讯作者）
Dongyang Jiang#*, Hao Liu#, Guofu Zhu#, Xiankai Li, Linlin Fan, Ze Yu, Shumin Wang, Jordan Rhen, Yiheng Yin, Yuling Gu, Xiangbin Xu, Edward A. Fisher, Junbo Ge, Yawei Xu*, Jinjiang Pang*. Endothelial PHACTR1 promotes endothelial activation and atherosclerosis by repressing PPARγ activity under disturbed flow in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023 Aug;43(8):e303-e322.
Linlin Fan#, Hao Liu, Guofu Zhu, Shekhar Singh, Ze Yu, Shumin Wang, Hong Luo, Shiying Liu, Yawei Xu, Junbo Ge*, Dongyang Jiang*, Jinjiang Pang*. Caspase-4/11 is critical for angiogenesis by repressing Notch1 signaling via inhibiting γ-secretase activity. British Journal of Pharmacology. 2022 Oct;179(20):4809-4828.
Qianqian Wang#, Dongyang Jiang#, Qing Ye#, Wenjing Zhou#, Junfan Ma, Chong Wang, Zihan Geng, Ming Chu, Jie Zheng, Hongchengcheng Chen, Jing Huang, Hui Dai, Youhui Zhang, Zhan-Long She, Ning Fu*, Xiaoyan Qiu*. A widely expressed free immunoglobulin κ chain with a unique Vκ4-1/Jκ3 pattern promotes colon cancer invasion and metastasis by activating the integrin β1/FAK pathway. Cancer Letters. 2022 Aug 1;540:215720.
Shumin Wang#, Guofu Zhu#, Dongyang Jiang#, Jordan Rhen, Xiankai Li, Hao Liu, Yuyan Lyu, Patrick Tsai, Yara Rose, Tiffany Nguyen, R. James White, Gloria S. Pryhuber, Thomas J. Mariani, Chen Li, Amy Mohan, Yawei Xu, Jinjiang Pang*. Reduced Notch1 cleavage promotes the development of pulmonary hypertension. Hypertension. 2022;79:79–92.
Dongyang Jiang#, Jianhui Zhuang#, Wenhui Peng, Yuyan Lu, Hao Liu, Qian Zhao, Chen Chi, Xiankai Li, Guofu Zhu, Xiangbin Xu, Chen Yan, Yawei Xu, Junbo Ge, Jinjiang Pang*. Phospholipase Cγ1 mediates intima formation through Akt-Notch1 signaling independent of the phospholipase activity. Journal of the American Heart Association. 2017, 6(7): e005537.
Dongyang Jiang#, Jing Ge, Qinyuan Liao, Junfan Ma, Yang Liu, Jing Huang, Chong Wang, Weiyan Xu, Jie Zheng, Wenwei Shao, Gregory Lee, Xiaoyan Qiu*. IgG and IgA with potential microbial-binding activity are expressed by normal human skin epidermal cells. International Journal of Molecular Sciences. 2015, 16(2): 2574-2590.
