杨维涛,59599aa美高梅副教授,博士生导师,2017年博士毕业于天津大学,目前担任生物医学工程与纳米科学研究院秘书,上海市催化医学前沿科学研究基地骨干。近年来聚焦分子影像探针在恶性肿瘤早期诊断中灵敏度和特异性不足等关键科学问题,开展了一系列研究。获得国自然面上项目、国自然青年项目、上海市面上、上海市卫健委临床研究专项、美高梅自主原创基础研究等项目资助。近年来,以第一/共一/通讯作者在ACS Nano, Biomaterials, Trends on Analytical Chemistry, Chemical Engineering Journal, Small等国际期刊上发表SCI论文20余篇(其中IF>10的13篇,部分入选封面和ESI前1%高被引),并授权4项国家发明专利,担任Exploration, Interdisciplinary Medicine期刊青年编委,获得首届同医最美科技工作者等称号。研究方向为生物医学材料(含小分子)功能设计、合成及其肿瘤诊疗应用。承担博士生课程《医学影像学技术与分子探针》、《实验动物学》以及本科生课程《五彩缤纷的发光材料》。
教育经历:
2012.09—2017.06 天津大学 材料学 工学博士 (导师:常津教授)
2016.12—2017.03 柏林自由大学 生物化学药学院 国家公派
2008.09—2012.07 青岛科技大学 高分子科学与工程 工学学士
工作经历:
2022.03-至今 美高梅 美高梅 副教授
2019.05-2022.02 美高梅 美高梅 副研究员
2017.06-2019.05 美高梅 美高梅 博士后(2019年美高梅优秀出站博后)
科研项目:
1. 国家自然科学基金面上项目,在研,主持;
2. 国家自然科学基金青年项目,结题,主持;
3. 上海市自然科学基金面上项目,结题,主持;
4. 上海市卫健委临床研究专项,结题,主持;
5. 中国博士后科学基金面上项目,结题,主持。
代表性论文:
1. Zhuoyao Wu, Weitao Yang*, and Bingbo Zhang*. Enzyme-Catalyzed Molecular MR Imaging of Tumor, Trends on Analytical Chemistry, 2024, 178, 117848.
2. Weitao Yang#, Cuijun Deng#, Xiudong Shi#, Yan Xu, Chenyu Dai, Hui Wang, Kexin Bian, Tianming Cui, and Bingbo Zhang*. Structural and Molecular Fusion MRI Nanoprobe for Differential Diagnosis of Malignant Tumors and Follow-Up Chemodynamic Therapy. ACS Nano, 2023, 17(4), 4009–4022.
3. Xiaoxv Geng, Kaixin Liu, Pengyuan Li, Huizhen Xing, Xiaoying Pei, Jin Chang*, Weitao Yang*, Xiaoli Wu*. A Multipronged Strategy for Encephalitis: Oxidative Stress Reduction and Inflammatory Microenvironment Modulation by a Neuroprotective Selenium-based Nanomedicine. Chemical Engineering Journal, 2024, 492, 152176.
4. Kaixin Liu, Shujun Chen, Xiaoxv Geng, Xiaoying Pei, Huizhen Xing, Xueying Zhang, Jin Chang, Weitao Yang*, and Xiaoli Wu*. Multifunctional Selenium-Based Metal Polyphenol Nanoparticles Impede the Pathological Cross-talk Between Reactive Oxygen Species and Inflammation in Sepsis. ACS Materials Letters, 2024, 6, 2434–2445.
5. Weitao Yang, Xiudong Shi, Yuxin Shi, Defan Yao, Shizhen Chen, Xin Zhou, and Bingbo Zhang*, Beyond the Roles in Biomimetic Chemistry: An Insight into the Intrinsic Catalytic Activity of an Enzyme for Tumor-Selective Phototheranostics, ACS Nano, 2018, 12 (12): 12169-12180.
6. Weitao Yang#, Weisheng Guo#, Wenjun Le, Guoxian Lv, Fuhe Zhang, Lei Shi, Xiuli Wang, Jun Wang, Sheng Wang, Jin Chang*, and Bingbo Zhang*. Albumin-Bioinspired Gd:CuS Nanotheranostic Agent for In Vivo Photoacoustic/Magnetic Resonance Imaging-Guided Tumor-Targeted Photothermal Therapy, ACS Nano, 2016, 10(11): 10245-10257.
7. Weitao Yang#, Chenyang Xiang#, Yan Xu, Shizhen Chen, Weiwei Zeng, Kai Liu, Xiao Jin, Xin Zhou*, and Bingbo Zhang*, Albumin-constrained large-scale synthesis of renal clearable ferrous sulfide quantum dots for T1-Weighted MR imaging and phototheranostics of tumors. Biomaterials, 2020, 255, 120186.
8. Weitao Yang, Xiaoli Wu, Yan Dou, Jin Chang*, Chenyang Xiang, Jiani Yu, JunWang, Xiuli Wang, Bingbo Zhang*, A human endogenous protein exerts multi-role biomimetic chemistry in synthesis of paramagnetic gold nanostructures for tumor bimodal imaging, Biomaterials, 2018, 161: 256-269.
9. Weitao Yang, Weisheng Guo, Xiaoqun Gong, Bingbo Zhang*, Sheng Wang, Na Chen, Wentao Yang, Yu Tu, Xiangming Fang, and Jin Chang*, Facile Synthesis of Gd-Cu-In-S/ZnS Bimodal Quantum Dots with Optimized Properties for Tumor Targeted Fluorescence/MR in Vivo Imaging. ACS Applied Materials & Interfaces, 2015, 7(33): 18759-18768.
10. Weitao Yang, Bingbo Zhang*, Porphyrin-based nanocomposites for tumor photodynamic therapy. MRS Bulletin, 2019, 44(3), 189-194.
11. Weitao Yang#, Weisheng Guo#, Jin Chang*, Bingbo Zhang*. Protein/peptide-templated biomimetic synthesis of inorganic nanoparticles for biomedical applications. Journal of Materials Chemistry B, 2017, 5, 401-417